| 1 | Permian High SchoolODESSA | High | 4,126 |
| 2 | Odessa High SchoolODESSA | High | 3,769 |
| 3 | Ector College Prep Success AcademyODESSA | Middle | 1,369 |
| 4 | Nimitz MiddleODESSA | Middle | 1,312 |
| 5 | Wilson & Young Medal of Honor MiddleODESSA | Middle | 1,193 |
| 6 | Murry Fly Elementary SchoolODESSA | Primary | 1,089 |
| 7 | Crockett MiddleODESSA | Middle | 1,019 |
| 8 | Barbara Jordan Elementary SchoolODESSA | Primary | 886 |
| 9 | Bowie MiddleODESSA | Middle | 872 |
| 10 | Bonham MiddleODESSA | Middle | 870 |
| 11 | Lee Buice Elementary SchoolODESSA | Primary | 821 |
| 12 | Edward K Downing Elementary SchoolODESSA | Primary | 807 |
| 13 | The STEM AcademyODESSA | Other | 743 |
| 14 | El Magnet at BlackshearODESSA | Primary | 693 |
| 15 | G E 'buddy' West Elementary SchoolODESSA | Primary | 683 |
| 16 | Lauro Cavazos Elementary SchoolODESSA | Primary | 674 |
| 17 | El Magnet at Reagan Elementary SchoolODESSA | Primary | 662 |
| 18 | Goliad Elementary SchoolODESSA | Primary | 616 |
| 19 | El Magnet at Milam Elementary SchoolODESSA | Primary | 605 |
| 20 | Dowling Elementary SchoolODESSA | Primary | 594 |
| 21 | Cameron Dual Language MagnetODESSA | Primary | 590 |
| 22 | Pease Elementary SchoolODESSA | Primary | 579 |
| 23 | Austin Montessori MagnetODESSA | Primary | 553 |
| 24 | Blanton Elementary SchoolODESSA | Primary | 522 |
| 25 | L B Johnson Elementary SchoolODESSA | Primary | 510 |
| 26 | El Magnet at HaysODESSA | Primary | 497 |
| 27 | Noel Elementary SchoolODESSA | Primary | 490 |
| 28 | Gonzales Elementary SchoolODESSA | Primary | 477 |
| 29 | Odessa Collegiate Academy Early College High SchoolODESSA | High | 460 |
| 30 | George H W Bush New Tech OdessaODESSA | High | 448 |
| 31 | El Magnet at ZavalaODESSA | Primary | 436 |
| 32 | Lamar Early Ee-KGODESSA | -- | 436 |
| 33 | Ireland Elementary SchoolODESSA | Primary | 424 |
| 34 | Ross Elementary SchoolODESSA | Primary | 422 |
| 35 | Sam Houston Elementary SchoolODESSA | Primary | 412 |
| 36 | Odessa Career and Technical Early College High SchoolODESSA | High | 395 |
| 37 | Burleson Elementary SchoolODESSA | Primary | 381 |
| 38 | San Jacinto Elementary SchoolODESSA | Primary | 375 |
| 39 | Carver Early Ee-KGODESSA | -- | 357 |
| 40 | Burnet Elementary SchoolODESSA | Primary | 340 |
| 41 | Gale Pond Alamo Elementary SchoolODESSA | Primary | 324 |
| 42 | El Magnet at TravisODESSA | Primary | 292 |
| 43 | The Odessa Y Learning CenterODESSA | -- | 186 |
| 44 | Alter Ed CenterODESSA | High | 100 |
| 45 | Ector Co Youth CenterODESSA | -- | 15 |
| 46 | Reg Day School for DeafODESSA | -- | 2 |